The facility will initially treat 7m3/s of wastewater coming from some five million citizens spread over 27 districts.
In a second phase, slated for July 2013, the plant's capacity will double to 14m3/s, enough to treat 85% of the blackwater collected through Lima's sewer network.
A consortium comprised of Spanish firms ACS and Tedagua won the concession to design, finance, build, operate and maintain the plant for 25 years in February 2009.
The construction phase required a total 416mn soles, Manche said.
The plant will put an end to the direct dumping of wastewater from eight discharge points leading to the Rímac river and the sea.